ea0056gp187 | Pituitary / Growth Hormone ' IGF Axis | ECE2018
Sugano Hisashi
, Kitamura Wataru
, Urata Tomoyuki
, Okamoto Taku
, Numoto Kunihiko
, Maruyoshi Natsue
Introduction: Erdheim-Chester disease (ECD) is a rare and aggressive form of non-Langerhans cell histiocytosis (n-LCH). Its etiology is unknown, but recently, BRAFV600E (a proto-oncogene) has been found in more than 50% of cases. This may play a part in chronic uncontrolled inflammation, which is an important aspect of disease pathogenesis.Case report: A 42-year-old woman complained of generalized weakness, polyuria, and secondary amenorrhea. Biochemistr...